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bromisoval
|Section2= |Section6= |Section8= }} Bromisoval (INN), commonly known as bromvalerylurea, is a hypnotic and sedative of the bromoureide group discovered by Knoll in 1907 and patented in 1909.〔 〕 It is marketed over the counter in Asia under various trade names (such as ''Brovarin''〔 (【引用サイトリンク】 Bromisoval )〕), usually in combination with non-steroidal anti-inflammatory drugs. Chronic use of bromisoval has been associated with bromine poisoning. Bromovisal can be prepared by bromination of isovaleric acid by the Hell-Volhard-Zelinsky reaction followed by reaction with urea. ==See also==
* Acecarbromal * Carbromal * Apronal
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