|
|Section2= |Section7= }} Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone. Examples include: * Haloperidol, the most widely used classical antipsychotic drug in this class〔 * Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment * Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine)〔 * Triperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) * Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients * Lenperone * Azaperone, used in veterinary medicine * Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). * Fluanisone * Penfluridol * Pipamperone * Spiperone (more potent neuroleptic than benperidol)〔Chronicles of Drug Discovery Vol 2〕 * Nonaperone The atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis. Ketocaine is a butyrophenone local anesthetic. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「butyrophenone」の詳細全文を読む スポンサード リンク
|