| 翻訳と辞書 |
canrenone
Canrenone (INN, USAN) (brand names Contaren, Luvion, Phanurane, Spiroletan) is a steroidal antimineralocorticoid and weak antiandrogen and progestogen related to spironolactone which is used as a diuretic in Europe.
Carenone is a major active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is believed to be partially or largely responsible for their effects.
Canrenone is more potent as an antimineralocorticoid relative to spironolactone, but is considerably less potent and effective as an antiandrogen. Similarly to spironolactone, canrenone inhibits steroidogenic enzymes such as 11β-hydroxylase, cholesterol side-chain cleavage enzyme, 17α-hydroxylase, and 21-hydroxylase, but once again, is comparatively more potent in doing so.
Canrenone has been found to be effective in the treatment of hirsutism in women.
==See also==
* Potassium canrenoate
* Prorenone
* Eplerenone
* Drospirenone
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「canrenone」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|