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centrocyte
A centrocyte generally refers to a B cell with a cleaved nucleus,〔() Stedman's Medical Dictionary. 2006〕 as may appear in e.g. follicular lymphoma.〔Table 12-8 in: 8th edition.〕
During B cell development, centrocytes are formed following the cessation of centroblast proliferation. Centrocytes test their newly mutated anti-binding sites (CDR loops) by re-expressing antigen on their surface.
Centrocyte can also refer to a cell with a protoplasm that contains single and double granules of varying size stainable with hematoxylin, as seen in lesions of lichen planus,〔 or a nondividing, activated B cell that expresses membrane immunoglobulin.〔
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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