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chalcone : ウィキペディア英語版
chalcone

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Chalcone is an aromatic ketone and an enone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones or chalconoids. Benzylideneacetophenone is the parent member of the chalcone series. The alternative name given to chalcone are phenyl styryl ketone, benzalacetophenone, ''β''-phenylacrylophenone, ''ɣ''-oxo-''α'',''ɣ''-diphenyl-''α''-propylene and ''α''-phenyl-''β''-benzoylethylene.
Chalcones and their derivatives demonstrate wide range of biological activities such as anti-diabetic, anti-neoplastic, anti-hypertensive, anti-retroviral, anti-inflammatory, anti-parasital, anti-histaminic, anti-malarial, anti-oxidant, anti-fungal, anti-obesity, anti-platelet, anti-tubercular, immunosuppressant, anti-arrhythmic, hypnotic, anti-gout, anxiolytic, anti-spasmodic, anti-nociceptive, hypolipidemic, anti-filarial, anti-angiogenic, anti-protozoal, anti-bacterial, anti-steroidal, etc.〔Mahapatra DK, Asati V, Bharti SK. Chalcones and their role in management of
diabetes mellitus: Structural and pharmacological perspectives. European Journal of Medicinal Chemistry 2015; 92, 839-865. DOI: 10.1016/j.ejmech.2015.01.051〕 〔Mahapatra DK, Bharti SK, Asati V. Anti-cancer Chalcones: Structural and Molecular Target Perspectives. European Journal of Medicinal Chemistry 2015, 98, 69-114. DOI: 10.1016/j.ejmech.2015.05.004.〕 〔Mahapatra DK, Bharti SK, Asati V. Chalcone scaffolds as anti-infective agents: Structural and molecular target perspectives. European Journal of Medicinal Chemistry 2015; 101, 496-524. DOI: 10.1016/j.ejmech.2015.06.052.〕
== Chemical properties ==
Chalcones have two absorption maxima at 280 nm and 340 nm.〔Photochemistry of chalcone and the application of chalcone-derivatives in photo-alignment layer of liquid crystal display. Dong-mee Song, Kyoung-hoon Jung, Ji-hye Moon and Dong-myung Shin, Optical Materials, 2002, volume 21, pages 667–671, 〕

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