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|Section2= |Section3= }} Citrinin is a mycotoxin originally isolated in 1931 by Hetherington and Raistrick from a culture of ''Penicillium citrinum''. It has since been found to be produced by a variety of other fungi that are found or used in the production of human foods, such as grain, cheese, sake, and red pigments. Citrinin has also been found in commercial red yeast rice supplements. ==Toxicity== Citrinin acts as a nephrotoxin in all species in which it has been tested, but its acute toxicity varies. It causes mycotoxic nephropathy in livestock and has been implicated as a cause of Balkan nephropathy and a form of cardiac beriberi (often referred to as "yellow rice disease" or "shoshin-kakke") in humans. Citrinin is used as a reagent in biological research. It induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex III of the respiratory chain. Citrinin can permeate through the human skin. Although no significant health risk is expected after dermal contact in agricultural or residential environments, dermal exposure should nevertheless be limited. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「citrinin」の詳細全文を読む スポンサード リンク
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