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Clioquinol (iodochlorhydroxyquin) is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication. The drugs have been found to have activity against both viral and protozoal infections. ==Antiprotozoal use== A 1964 report described the use of Clioquinol in both the treatment and prevention of shigella infection and ''Entamoeba histolytica'' infection in institutionalized individuals at Sonoma State Hospital in California. The report indicates 4000 individuals were treated over a 4-year period with few side effects. Several recently reported journal articles describing its use as an antiprotozoal include: * A 2005 reference to its use in treating a Dutch family for ''Entamoeba histolytica'' infection. * A 2004 reference to its use in the Netherlands in the treatment of ''Dientamoeba fragilis'' infection. * A 1979 reference to the use in Zaire in the treatment of ''Entamoeba histolytica'' infection. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「clioquinol」の詳細全文を読む スポンサード リンク
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