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codeinone
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Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone, a painkiller roughly half again more or up to 1.7× the strength of morphine.〔(Synthesis of Oxycodone from Codeine. ) Aug 2004 static snapshot of Rhodium site archive hosted by Erowid, May 2005〕 The latter can also be synthesized from thebaine, however.〔(Oxycodone / 14-hydroxydihydrocodeinone Synthesis; with alternative synthesis of 14-hydroxycodeinone intermediate. ) J. Med. Chem., 1974, 17, 1117〕
==Chemical structure==
Codeinone can be described as the methylether of morphinone: 3-methyl-morphinone.
Codeinone can be also described as the ketone of codeine: codeine-6-one.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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