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conessine : ウィキペディア英語版
conessine

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Conessine is a steroid alkaloid found in a number of plant species from the ''Apocynaceae'' family, including ''Holarrhena floribunda'', ''Holarrhena antidysenterica'' and ''Funtumia elastica''. It acts as a histamine antagonist, selective for the H3 subtype (with an affinity of pKi = 8.27; Ki = ~5 nM). It was also found to have long CNS clearance times, high blood-brain barrier penetration and high affinity for the adrenergic receptors.
== References ==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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