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desipramine
Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA). It inhibits the reuptake of norepinephrine and to a minor extent serotonin. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. It is sold under the brand names Norpramin, and Pertofrane.
==Medical uses==
It is primarily used for the treatment of depression.〔 It may also be useful to treat symptoms of attention deficit hyperactivity disorder. Evidence of benefit is only in the short term and with concerns of side effects its overall usefulness is not clear. Desipramine at very low doses is also used to help reduce the pain associated with functional dyspepsia. 〔http://www.uptodate.com/contents/upset-stomach-functional-dyspepsia-in-adults-beyond-the-basics〕
It has also been tried, albeit with little evidence of efficacy, in the treatment of cocaine dependence. Evidence for usefulness in neuropathic pain is also poor.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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