|
Dicloxacillin (INN) is a narrow-spectrum β-Lactam antibiotic of the penicillin class.〔 It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria.〔Product Information: DICLOXACILLIN SODIUM-dicloxacillin sodium capsule. Teva Pharmaceuticals USA Inc, Revised 8/2015〕 It is active against beta-lactamase-producing organisms such as ''Staphylococcus aureus'', which would otherwise be resistant to most penicillins. Dicloxacillin is available under a variety of trade names including Diclocil (BMS). ==Medical uses== Dicloxacillin is used to treat mild-to-moderate staphylococcal infections.〔"Dicloxacillin". ''livertox.nih.gov''. Retrieved 2015-11-05.〕 To decrease the development of resistance, dicloxacillin is recommended to treat infections that are suspected or proven to be caused by beta-lactamase-producing bacteria.〔 Dicloxacillin has similar pharmacokinetics, antibacterial activity, and indications to flucloxacillin, and the two agents are considered interchangeable.〔Rossi S, editor. Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006〕 It is believed to have lower incidence of severe hepatic adverse effects than flucloxacillin, but a higher incidence of renal adverse effects.〔 Dicloxacillin is used for the treatment of infections caused by susceptible bacteria. Specific approved indications include:〔 *Staphylococcal skin infections and cellulitis – including impetigo, otitis externa, folliculitis, boils, carbuncles, and mastitis *Pneumonia (adjunct) *Osteomyelitis, septic arthritis, throat infections, streptococcus *Septicaemia *Empirical treatment for endocarditis *Surgical prophylaxis 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「dicloxacillin」の詳細全文を読む スポンサード リンク
|