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Dysdiadochokinesia, dysdiadochokinesis, dysdiadokokinesia, dysdiadokokinesis (from Greek ''δυς'' ''dys'' "bad", ''διάδοχος'' ''diadochos'' "succeeding", ''κίνησις'' ''kinesis'' "movement"), often abbreviated as DDK, is the medical term for an impaired ability to perform rapid, alternating movements (i.e. diadochokinesia). Complete inability is called adiadochokinesia. ==Causes== Dysdiadochokinesia is a feature of cerebellar ataxia and may be the result of lesions to either the cerebellar hemispheres or the frontal lobe (of the cerebrum), it can also be a combination of both. It is thought to be caused by the inability to switch on and switch off antagonising muscle groups in a coordinated fashion due to hypotonia, secondary to the central lesion.〔("Dysdiadochokinesia" ), ''UBM Medica'', United States. (2011). Retrieved May 11, 2011.〕 Dysdiadochokinesia is also seen in Friedreich's ataxia and multiple sclerosis, as a cerebellar symptom (including ataxia, intention tremor and dysarthria). It is also a feature of ataxic dysarthria. Dysdiadochokinesia often presents in motor speech disorders (dysarthria), therefore testing for dysdiadochokinesia can be used for a differential diagnosis.〔 Dysdiadochokinesia has been linked to a mutation in ''SLC18A2'', which encodes vesicular monoamine transporter 2 (''VMAT2''). Tests are often done in medical surgeries to establish the patient's levels of dysdiadochokinesia, with one being the ability to change the orientation of the hand flat on the other hand. A human without impaired coordination would be expected to be able to carry out the test, however exceptions must be made. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「dysdiadochokinesia」の詳細全文を読む スポンサード リンク
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