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furosemide
Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/furosemide.html )〕 It may also be used for the treatment of high blood pressure. The amount of medication required depends on the person in question. It can be taken intravenously or by mouth. When taken by mouth it typically begins working within an hour while intravenously it typically begins working within five minutes.〔
Common side effects include low blood pressure with standing, ringing in the ears, and sensitivity to the sun. Potentially serious side effects include electrolyte abnormalities, low blood pressure, and hearing loss. Blood tests are recommended regularly for those on treatment. Furosemide is a type of loop diuretic that works by decreasing the reabsorption of sodium by the kidneys.〔
Furosemide was discovered in 1962. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The global wholesale price is between 0.004 and 0.02 USD per day.〔(【引用サイトリンク】url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=FUR40T&s_year=2014&year=2014&str=40%20mg&desc=Furosemide&pack=new&frm=TAB-CAP&rte=PO&class_code2=16%2E&supplement=&class_name=%2812%2E4%2E%29Medicines%20used%20in%20heart%20failure%3Cbr%3E%2816%2E%29Diuretics%3Cbr%3E )〕 In the United States it is available as a generic medication and costs about 0.15 USD per day.〔 Furosemide is on the World Anti-Doping Agency's banned drug list due to concerns that it may mask other drugs. It has also been used to prevent and treat race horses for exercise-induced pulmonary hemorrhage.
==Medical uses==
Furosemide is primarily used for the treatment of hypertension and edema.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/furosemide.html )〕 It is the first-line agent in most people with edema caused by congestive heart failure.〔 It is also used for hepatic cirrhosis, renal impairment, nephrotic syndrome, in adjunct therapy for cerebral or pulmonary edema where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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