|
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.〔''The American Heritage Medical Dictionary'', 2007, Houghton Mifflin Company〕 The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method that animals use to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. Enzymes that cleave the glycosidic bond of a glucuronide are called glucuronidases. == Examples == * Miquelianin (Quercetin 3-O-glucuronide) * Morphine-6-glucuronide * Ezetimibe (Prodrug) * Scutellarein-7-glucuronide 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「glucuronide」の詳細全文を読む スポンサード リンク
|