| 翻訳と辞書 |
harmane
Harmane (harman) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee〔(Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee ) Life Sci. 2006 Jan 18;78(8):795-802. Epub 2005 Aug 31.〕 and tobacco smoke.〔(Human monoamine oxidase is inhibited by tobacco smoke: β-carboline alkaloids act as potent and reversible inhibitors ) Biochemical and Biophysical Research Communications Volume 326, Issue 2, 14 January 2005, Pages 378–386.〕 Harmane is strongly associated with Essential Tremor, one of the most common neurological diseases in the elderly.〔(Elevation of blood ''beta''-carboline alkaloids in essential tremor ) http://web.ics.purdue.edu/~wzheng/Publications/Epapers/2002_Louis%20et%20al%20Neurology.pdf〕 It is likely to be the main endogenous ligand for the benzodiazepine receptor. 〔(1-Methyl-beta-carboline (harmane), a potent endogenous inhibitor of benzodiazepine receptor binding ) Naunyn Schmiedebergs Arch. Pharmacol. 1980 Oct;314(1):97-100〕 Highest concentrations are found in cooked meat (chicken, beef, pork and fish).
== See also ==
* Harmine
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「harmane」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|