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hyperforin
Hyperforin is a phytochemical produced by some of the members of the plant genus ''Hypericum'', notably ''Hypericum perforatum'' (St John's wort). Hyperforin (along with adhyperforin) is believed to be one of the three chief active constituents of St. John's wort -the other two being hypericin (along with pseudohypericin) and several flavonoid constituents.〔https://www.liebertpub.com/DContent/Files/SampleChapters/Sample_BotanicalMedicineFromBenchtoBeds.pdf〕 == Occurrence == Hyperforin has only been found in significant amounts in ''Hypericum perforatum'' (St. John's wort) with other related species such as ''Hypericum calycinum'' (Greater St. John's wort or Aaron's beard) containing lower levels of the phytochemical. It is thought to be a reuptake inhibitor. It accumulates in oil glands, pistils, and fruits, probably as a plant defense against herbivory.〔Beerhues L. (2006). "Hyperforin." ''Phytochemistry'' 67 (20): 2201-7. PMID 16973193〕 Other ''Hypericum'' species contain low amounts of hyperforin.
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