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Indometacin (INN and BAN) or indomethacin (AAN, USAN and former BAN) is a non-steroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms. It is marketed under more than twelve different trade names.〔Trade names are listed on (DrugBank.ca ) entry DB00328〕 == Medical uses == Clinical indications for indometacin include: * Hemicrania continua〔Garza, I & Schwedt, TJ. "Hemicrania continua." UpToDate. http://www.uptodate.com/contents/hemicrania-continua. Accessed 8/27/13.〕 * ankylosing spondylitis * arthritic gout * Bartter syndrome * bursitis * cryoglobulinemia * dysmenorrhea (menstrual cramps) * exertion headache * fever and pain associated with malignant diseases (especially tumor fever associated with liver involvement, lymphogranulomatosis) * hypnic headache * juvenile arthritis * migraine * patent ductus arteriosus * nephrogenic diabetes insipidus (prostaglandin inhibits vasopressin's action in the kidney) * osteoarthritis * Paget's disease of bone * paroxysmal hemicrania〔 * pericarditis * primary stabbing headaches〔 * pseudogout * psoriatic arthritis * Reactive arthritis * renal colic (pain due to kidney stones) * retinopathy of prematurity * rheumatoid arthritis * tendinitis * trigeminal autonomic cephalgias〔 * Headaches caused by the Valsalva maneuver Indomethacin has also been used clinically to delay premature labor, reduce amniotic fluid in polyhydramnios, and to close patent ductus arteriosus. Indomethacin is a potent drug with many serious side effects and should not be considered an analgesic for minor aches and pains or fever. The medication is better described as an anti-inflammatory, rather than an analgesic. Indomethacin can also affect warfarin and subsequently raise INR. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「indometacin」の詳細全文を読む スポンサード リンク
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