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Isoprenaline (INN) or isoproterenol (USAN, trade names Medihaler-Iso and Isuprel) is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma. In humans, it is a non-selective beta-adrenergic agonist and TAAR1 agonist that is structurally similar to adrenaline.〔 "(Table 1: EC50 values of different agonists at hTAAR1, hADRB1 and hADRB2. )"〕 ==Uses== Its primary use is for bradycardia or heart block. By activating β1-receptors in the heart, it induces positive chronotropic, dromotropic, and inotropic effects.〔 It can be used as an inhaled aerosol to treat asthma, although this is currently a rare treatment.〔 Although it activates all beta adrenergic receptors, it works in a similar fashion to selective β2-adrenergic agonists e.g. salbutamol, by relaxing the airways to increase airflow. It is also supplied in ampoules under the brand name Isuprel for injection and in sublingual pill form for treatment of asthma, chronic bronchitis and emphysema. Used with caution, it can also be used to treat torsades de pointes by acquired defect, in conjunction with overdrive pacing and magnesium sulfate. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「isoprenaline」の詳細全文を読む スポンサード リンク
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