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iteron
Iterons are directly repeated DNA sequences which play an important role in regulation of plasmid copy number in bacterial cells. It is one among the three negative regulatory elements found in plasmids which control its copy number, the others being antisense RNAs and ctRNAs. Iterons complex with cognate replication (Rep) initiator proteins to achieve the required regulatory effect.〔〔 ==Regulation of Replication==
Iterons have an important role in plasmid replication. An iteron-containing plasmid origin of replication can be found containing about five iterons about 20 base pairs in length total. These iterons provide a saturation site for initiator receptor proteins and promote replication thus increasing plasmid copy number in a given cell.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「iteron」の詳細全文を読む
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