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khellin : ウィキペディア英語版
khellin

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Khellin has been used as an herbal folk medicine, with use in the Mediterranean dating back to Ancient Egypt, to treat a variety of maladies including: renal colic, kidney stones, coronary disease, bronchial asthma, vitiligo, and psoriasis. It is a major constituent of the plant ''Ammi visnaga'', also known as Bishop's Weed. Once purified, khellin exists as colorless, odorless, bitter-tasting needle-shaped crystals and is classified as a gamma-pyrone, a furanochromone derivative. In the early 20th century, researchers searched for khellin analogs with lower toxicity and better efficacy. A number of drugs were discovered through this research, such as amiodarone and cromolyn sodium, which are used in current medical practice.
==Background==
Khellin is found in Egypt, the Middle East, and areas surrounding the Mediterranean. It is a major constituent of the plant ''Ammi Visnaga'', existing between 0.3 and 1.2% in the leaves and seeds. Bishop's Weed is a name given to several species of plants; however, only ''Ammi Visnaga'' contains khellin.
Khellin is rarely found in its pure form; instead it is found in Ammi Visnaga or "Khella" extract. As a result, many healing properties have been attributed to Khellin that are actually due to other constituents in the extract.
Ammi Visnaga preparations are commercially available and very common; however, the amount of Khellin and other ingredients varies greatly between brands and even batches of the same brand. The extract is commonly found as a tea or in a pill form.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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