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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク langerin ： ウィキペディア英語版 langerin CD207, langerin (Cluster of Differentiation 207) is a protein which in humans is encoded by the ''CD207'' gene.〔 Langerin is a type II transmembrane, C-type lectin receptor on Langerhans cells.〔 ==Function== The protein encoded by this gene is expressed in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Additionally it is known by the name ''C-type lectin domain family 4 member K (CD antigen ''CD207'')''. It is also expressed in several other dendritic cell types including dermal CD103+ DCs and splenic CD8+ DCs. Langerin is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「langerin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.