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lapachol : ウィキペディア英語版
lapachol

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Lapachol is a natural phenolic compound isolated from the bark of the lapacho tree.〔Record, Samuel J.. "Lapachol" pages 17-19. In: ''Tropical Woods'' (1925).〕 This tree is known botanically as ''Handroanthus impetiginosus'', but was formerly known by various other botanical names such as ''Tabebuia avellanedae''.〔 Susan O. Grose and Richard G. Olmstead. 2007. "Evolution of a Charismatic Neotropical Clade: Molecular Phylogeny of ''Tabebuia'' s.l., Crescentieae, and Allied Genera (Bignoniaceae)". ''Systematic Botany'' 32(3):650-659. 〕 Lapachol is also found in other species of ''Handroanthus''.
Lapachol is usually encountered as a yellow, skin-irritating powder from wood. Chemically, it is a derivative of vitamin K〔 Louis F.Fieser. ''The Scientific Method'' pages 163-191. Reinhold Publishing Corporation, New York, 1964〕
Once studied as a possible treatment for some types of cancer, it is now considered too toxic for use〔Oral toxicology studies with lapachol. Morrison, Robert K.; Brown, Donald Emerson; Oleson, Jerome J.; Cooney, David A. Toxicology and Applied Pharmacology (1970), 17(1), 1-11.〕
== See also ==

* Hooker reaction

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「lapachol」の詳細全文を読む



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