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leflunomide : ウィキペディア英語版
leflunomide

Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor.
==Medical use==
Rheumatoid arthritis and psoriatic arthritis are the only indications that have received regulatory approval.〔 Clinical studies regarding the following diseases have been conducted:〔http://clinicaltrials.gov/ct2/results?term=Leflunomide〕

* Polyoma BK Virus Nephropathy
* Kimura's disease
* Systemic lupus erythematosus
* Felty's syndrome
* Takayasu arteritis
* Granulomatosis with polyangiitis
* Ankylosing spondylitis
* Crohn's disease
* Sarcoidosis
* Uveitis
* Still's disease
* Prostate cancer
* Pemphigoid
* Prevention of organ transplant rejection

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「leflunomide」の詳細全文を読む



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