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matrine
Matrine is an alkaloid found in plants from the ''Sophora'' genus. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and µ-receptor agonist.
Matrine possesses strong antitumor activities ''in vitro'' and ''in vivo''. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Matrine is a component of the traditional Chinese medical herb ''Sophora flavescens'' Ait.
Mu opioid agonism is associated with euphoria, while kappa opioid agonism is associated with dysphoria and psychotomimetic hallucinations (as seen in the kappa-agonist Salvinorin A). Both receptors are known to produce analgesia when activated.
Matrine and the related compound oxymatrine have an antifeedant effect against Formosan subterranean termite.
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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