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medulloepithelioma
Medulloepithelioma is a rare, primitive, fast-growing brain tumour thought to stem from cells of the embryonic medullary cavity.〔(Definition of Medulloepithelioma ), from Online Medical Dictionary. Retrieved 7 January 2010.〕 Tumours originating in the ciliary body of the eye are referred to as embryonal medulloepitheliomas,〔 or diktyomas.〔McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.〕
A highly malignant undifferentiated primitive neuroepithelial tumour of children, medulloepithelioma may contain bone, cartilage, skeletal muscle, and tends to metastasize extracranially.〔
==Epidemiology==
Medulloepithelioma most commonly affect children between 6 months and 5 years; rarely, this tumour may occur congenitally or beyond this age range.〔Russel DS, Rubinstein LJ. Pathology of tumors the nervous system, 5th ed. Baltimore: Williams & Wilkins 1989; pp. 247-51.〕〔Sato T, Shimoda A, Takahishi T, et al. Congenital cerebellar neuroepithelial tumor with multiple divergent differentiation. Acta Neuropathol 1980;50:143-6.〕〔Scheithauer BW, Rubinstein LJ. Cerebral medulloepithelioma: Report of a case with multiple divergent neuroepithelial differentiation. Childs Brain 1979;5:62-71.〕 Incidence is equal in males and females.〔Molly PT, Yachnis AT, Rorke LB, et al. Central nervous system medulloepithelioma a series of eight cases including two arising in the pons. J Neurosurg 1996;84:430-6.〕
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