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methoxphenidine
Methoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury.〔(【引用サイトリンク】 title=Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury )〕 Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral potency. Of the three isomeric anisyl-substituents methoxphenidine has affinity for the NMDA receptor that is higher than 4-MeO-Diphenidine but lower than 3-MeO-Diphenidine,〔 a structure–activity relationship shared by the anisylcyclohexylamines.
== Side effects ==
Acute methoxphenidine intoxication has been reported to produce confusion, hypertension, and tachycardia that was responsive to treatment with intravenous lorazepam, methoxphenidine has also been associated with three published fatalities and one case of impaired driving.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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