|
Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug. It is marketed in the USA and Canada under the brand names Medrol and Solu-Medrol.〔(Methylprednisolone - Compound Summary ) PubChem〕 It is also available as a generic drug. It is a variant of prednisolone, methylated at carbon 6 of the B ring. ==Uses== Like most adrenocortical steroids, methylprednisolone is typically used for its anti-inflammatory effects. However, glucocorticoids have a wide range of effects, including changes to metabolism and immune responses. The list of medical conditions for which methylprednisolone is prescribed is rather long, and is similar to other corticosteroids such as prednisolone. Common uses include arthritis therapy and short-term treatment of bronchial inflammation or acute bronchitis due to various respiratory diseases. It is used both in the treatment of acute periods and long-term management of autoimmune diseases, most notably systemic lupus erythematosus. It is also used as a treatment for multiple sclerosis. Methylprednisolone is also prescribed for nonpenetrating spinal cord injuries. It has been shown that a dose of 30 mg/kg intravenously (IV) followed by IV drip at 5.4 mg/kg/h for 23 hours improves sensory and motor recovery if given within eight hours of the injury. It is also used for vestibular neuritis. After egg retrieval for a cycle of ''in vitro'' fertilization, methylprednisolone may be prescribed to prevent the body from rejecting the embryos being transferred, up to the time of implantation.〔(【引用サイトリンク】url=http://www.infertilityspecialistnewyork.com/ivf-what-to-expect-in-vitro-fertilization-manhattan-brooklyn-bronx-new-york-ny.htm )〕〔(【引用サイトリンク】url=http://www.rmami.com/treatments-female-ivf-troy-michigan.html )〕 Methylprednisolone may also be beneficial in the treatment of patients in cardiac arrest.〔http://archinte.jamanetwork.com/article.aspx?articleid=414696〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「methylprednisolone」の詳細全文を読む スポンサード リンク
|