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|Section2= |Section3= }} Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria that have been assigned a variety of species names including, ''M. ulcerans'', ''M. liflandii'' (an unofficial designation), ''M. pseudoshottsii'', and some strains of ''M. marinum''. These mycobacteria are collectively referred to as mycolactone-producing mycobacteria or MPM. In humans, mycolactone is the toxin responsible for Buruli ulcers, doing so by damaging tissues and inhibiting the immune response. ==Variants== Five distinct, naturally-occurring mycolactone structural variants have been described so far: * Mycolactone A/B (''M. ulcerans'' from Africa, Malaysia, Japan〔) * Mycolactone C (''M. ulcerans'' from Australia) * Mycolactone D (''M. ulcerans'' from China) * Mycolactone E (''M. liflandii'' from Sub-Saharan Africa) * Mycolactone F (''M. pseudoshottsii'' and ''M. marinum'' from around the world)〔 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「mycolactone」の詳細全文を読む スポンサード リンク
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