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nimesulide
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. It has a multifactorial mode of action and is characterized by a fast onset of action.
It works by blocking the production of prostaglandins (a chemical associated with pain) thereby relieving pain and inflammation.
==Medical uses==
* Nimesulide has similar gastrointestinal safety as compared to other NSAIDs.
* It may be taken through prescription in the treatment of Acute (short term) pain, and Primary dysmenorrhea (Period Pains). Nimesulide should never be taken long-term, such as for chronic conditions like arthritis. This is due to its association with an increased risk of liver toxicity, including fulminant hepatic failure.〔(【引用サイトリンク】url=http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/referrals/Nimesulide/human_referral_000275.jsp&mid=WC0b01ac0580024e9a )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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