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nitroimidazole : ウィキペディア英語版
nitroimidazole

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5-Nitroimidazole is an organic compound with the formula O2NC3H2N2H. It is the most common isomer of imidazole containing one nitro group. The term nitroimidazole also refers to a class of antibiotics that share similar chemical structures.〔 Edwards, David I. "Nitroimidazole drugs - action and resistance mechanisms. I. Mechanism of action" Journal of Antimicrobial Chemotherapy 1993, volume 31, pp. 9-20. .〕
==Synthesis==
Imidazole reacts with a mixture of nitric acid to give 5-nitroimidazole:
:C3H3N2H + HNO3 → O2NC3H2N2H + H2O
Under conventional conditions for nitration, the reaction is conducted in the presence of sulfuric acid.

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