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nociceptor A nociceptor is a sensory neuron (nerve cell) that responds to potentially damaging stimuli by sending signals to the spinal cord and brain. This process, called nociception, usually causes the perception of pain. ==History==
Nociceptors were discovered by Charles Scott Sherrington in 1906. In earlier centuries, scientists believed that animals were like mechanical devices that transformed the energy of sensory stimuli into motor responses. Sherrington used many different styles of experiments to demonstrate that different types of stimulation to a nerve's receptive field led to different responses. Some intense stimuli trigger reflex withdrawal, autonomic responses and pain. The specific receptors for these intense stimuli were called nociceptors.〔Sherrington C. The Integrative Action of the Nervous System. Oxford: Oxford University Press; 1906.〕
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