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obatoclax
|Section2= |Section3= |Section5= }} Obatoclax is an experimental drug candidate for the treatment of various types of cancer. It was discovered by Gemin X, which was acquired by Cephalon.〔(Cephalon Announces Definitive Agreement to Acquire Gemin X ), March 21, 2011〕 It is in Phase II clinical trials for the treatment of leukemia, lymphoma, myelofibrosis, and mastocytosis.〔(Gemin X Presents New Data on Obatoclax at the American Society of Hematology Meeting ), Dec 9, 2008〕〔(Obatoclax ) at ClinicalTrials.gov〕 ==Mechanism of action==
Obatoclax is an inhibitor of the Bcl-2 family of proteins. This inhibition induces apoptosis in cancer cells, preventing tumor growth.
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