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omptin : ウィキペディア英語版
omptin

Omptins (, ''protease VII'', ''protease A'', ''gene ompT proteins'', ''ompT protease'', ''protein a'', ''Pla'', ''OmpT'') are a family of bacterial proteases. They are aspartate proteases, which cleave peptides with the use of a water molecule. Found in the outer membrane of gram-negative enterobacteria such as ''Shigella flexneri'', ''Yersinia pestis'', ''Escherichia coli'', and ''Salmonella enterica''. Omptins consist of a widely conserved beta barrel spanning the membrane with 5 extra-cellular loops. These loops are responsible for the various substrate specificities. These proteases rely upon binding of lipopolysaccharide for activity.
Omptins have been linked with pathogenesis in several bacteria.〔
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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