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optochin : ウィキペディア英語版
optochin

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Optochin (or ethylhydrocupreine) is a chemical used in cell culture techniques for the presumptive identification of ''Streptococcus pneumoniae'', which is optochin-sensitive, from other alpha-hemolytic streptococci such as ''Streptococcus viridans'', which are resistant. A common mnemonic is "OVRPS" (Optochin - Viridans () Resistant, Pneumoniae () Sensitive). Or "VROPS" (Viridans Resistant () Optochin, Pneumoniae Sensitive)
The growth of bacteria that are optochin-sensitive will be inhibited around an optochin disc, while the growth of bacteria that are optochin-resistant will not be affected. In vitro, a solution of as little as 1:10,000,000 may be inhibitory to the pneumococcus, and 1:500,000 is bactericidal.〔http://chestofbooks.com/health/materia-medica-drugs/Pharmacology-Therapeutics-Prescription-Writing/Ethylhydrocupreine.html〕
==Resistance==
Strains of ''Streptococcus pneumoniae'' have been found to be resistant to optochin in laboratory testing.

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