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pamaquine
Pamaquine is an 8-aminoquinoline drug used for the treatment of malaria. It is closely related to primaquine.
==History==
Pamaquine was the second synthetic antimalarial drug to be discovered (after methylene blue). It was synthesised by Schulemann, Schoenhoeffer and Wingler in 1924. In 1926, Roehl demonstrated that pamaquine was effective in treating malaria in birds, and introduced it into use in humans.
A large trial of pamaquine performed by the Royal Army Medical Corps and the Indian Medical Corps in 1929 showed for the first time that it was possible to prevent relapse of vivax malaria. Prior to this, it was understood that patients with vivax malaria would suffer from relapses, but there was no treatment that could prevent the relapses from occurring.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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