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pempidine
Pempidine is a ganglion-blocking drug, first reported in 1958 by two research groups working independently, and introduced as an oral treatment for hypertension.〔A. Spinks and E. H. P. Young (1958) ''Nat.'' 181 1397〕〔G. E. Lee et al. (1958) ''Nat.'' 181 1717.〕 ==Pharmacology==
Reports on the "classical" pharmacology of pempidine have been published.〔A. Spinks et al. (1958) ''Br. J. Pharmacol. Chemother.'' 13 501-520.〕〔D. F. Muggleton and H. W.Reading (1959) ''Br. J. Pharmacol. Chemother.'' 14 202〕 The Spinks group, at ICI, compared pempidine, its N-ethyl analogue, and mecamylamine in considerable detail, with additional data related to several structurally simpler compounds.〔
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