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roflumilast : ウィキペディア英語版
roflumilast

Roflumilast (trade names Daxas, Daliresp) is a drug that acts as a selective, long-acting inhibitor of the enzyme PDE-4 (Phosphodiesterase-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD).
In June 2010, Daxas was approved in the EU for severe COPD associated with chronic bronchitis.〔("Nycomed's Anti-Inflammatory Gains Approval in EU for COPD" )〕 In March 2011, Daliresp gained FDA approval in the US for reducing COPD exacerbations.
==Medical uses==
Its primary clinical use is in the prevention of exacerbations (lung attacks) in severe COPD.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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