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Salicylmethylecgonine, (2′-Hydroxycocaine) is a tropane derivative drug which is both a synthetic analogue and a possible active metabolite of cocaine.〔Singh S, Basmadjian GP, Avor K, Pouw B, Seale TW. (A convenient synthesis of 2'- or 4'-hydroxycocaine. ) ''Synthetic Communications''. 1997;27(22):4003-4012.〕 Its potency ''in vitro'' is around 10x that of cocaine,〔el-Moselhy TF, Avor KS, Basmadjian GP. 2'-substituted analogs of cocaine: synthesis and dopamine transporter binding potencies. ''Archiv der Pharmazie (Weinheim)''. 2001 Sep;334(8-9):275-8. PMID 11688137〕 although it is only around three times more potent than cocaine when administered to mice.〔Seale TW, Avor K, Singh S, Hall N, Chan HM, Basmadjian GP. 2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding. ''Neuroreport''. 10 November 1997;8(16):3571-5. PMID 9427328〕 ==See also== * 2′-Acetoxycocaine * 4′-Fluorococaine * Benzoylecgonine * Ecgonine * Norcocaine * List of cocaine analogues 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「salicylmethylecgonine」の詳細全文を読む スポンサード リンク
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