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sclerodactyly
Sclerodactyly is a localized thickening and tightness of the skin of the fingers or toes. Sclerodactyly often leads to ulceration of the skin of the distal digits and is commonly accompanied by atrophy of the underlying soft tissues.
The term "sclerodactyly" is made up from the Greek "skleros" meaning hard and "daktylos" meaning a finger or toe – "hard fingers or toes".
It is sometimes associated with scleroderma and mixed connective tissue disease, auto-immune disorders.
Sclerodactyly is a component of the CREST variant of scleroderma (CREST is an acronym that stands for calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.)
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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