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somitomere
In the developing vertebrate embryo, the somitomeres (or somatomeres)are cells that are derived from the loose masses of paraxial mesoderm that are found alongside the developing neural tube. In human embryogenesis they appear towards the end of the third gestational week. The approximately 50 pairs of somitomeres in the human embryo, begin developing in the cranial (head) region, continuing in a caudal (tail) direction until the end of week four.
==Development==
The first seven somitomeres give rise to the striated muscles of the face, jaws, and throat.〔Larsen W.J. Human Embryology. Churchill Livingstone.Third edition 2001.Page 62. ISBN 0-443-06583-7〕
The remaining somitomeres, likely driven by periodic expression of the ''hairy'' gene, begin expressing adhesion proteins such as N-cadherin and fibronectin, compact, and bud off forming somites. The somites give rise to the vertebral column (sclerotome), associated muscles (myotome), and overlying dermis (dermatome).
There are a total of 37 somite pairs at the end of the fifth week of development, after the first occipital somite and 5-7 coccygeal somites disappear from the original 42-44 somites
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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