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subiculum
The subiculum (Latin for "support") is the most inferior component of the hippocampal formation. It lies between the entorhinal cortex and the CA1 subfield of the hippocampus proper.
==Structure==
It receives input from CA1 and entorhinal cortical layer III pyramidal neurons and is the main output of the hippocampus. The pyramidal neurons send projections to the nucleus accumbens, septal nuclei, prefrontal cortex, lateral hypothalamus, nucleus reuniens, mammillary nuclei, entorhinal cortex and amygdala.
The pyramidal neurons in the subiculum exhibit transitions between two modes of action potential output: bursting and single spiking.〔(Donald C. Cooper ), Sungkwon Chung, Nelson Spruston, "(Output-Mode Transitions Are Controlled by Prolonged Inactivation of Sodium Channels in Pyramidal Neurons of Subiculum )," ''PLoS Biology'', 3(6):e175, 2005 June.〕 The transitions between these two modes is thought to be important for routing information out of the hippocampus.
Four component areas have been described:〔http://atlas.brain-map.org〕 parasubiculum (adjacent to the parahippocampal gyrus), presubiculum, subiculum, and prosubiculum.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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