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sulfadoxine
Sulfadoxine (also spelled sulphadoxine) is an ultra-long-lasting sulfonamide previously used in combination with pyrimethamine to treat or prevent malaria.〔(Medical Treatment - Sulphadoxine and Pyrimethamine ).〕 Due to high levels of resistance, its use is no longer recommended routinely.
It is also used, usually in combination with other drugs, to treat or prevent various infections in livestock.〔http://en.scientificcommons.org/19483411.〕
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
==Mechanism of action==
Sulfadoxine competitively inhibits dihydropteroate synthase, interfering with folate synthesis.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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