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Tegafur (INN, BAN, USAN) is a chemotherapeutic fluorouracil prodrug used in the treatment of cancers. It is a component of the combination drug tegafur/uracil. When metabolised, it becomes 5-fluorouracil. ==Medical uses== As a prodrug to 5-FU it is used in the treatment of the following cancers: * Stomach (when combined with gimeracil and oteracil) * Breast (with uracil) * Gallbladder * Lung (specifically adenocarcinoma, typically with uracil) * Colorectal (usually when combined with gimeracil and oteracil) * Head and neck * Liver (with uracil) * Pancreatic It is often given in combination with drugs that alter its bioavailability and toxicity such as gimeracil, oteracil or uracil.〔 These agents achieve this by inhibiting the enzyme dihydropyrimidine dehydrogenase (uracil/gimeracil) or orotate phosphoribosyltransferase (oteracil).〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「tegafur」の詳細全文を読む スポンサード リンク
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