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temozolomide : ウィキペディア英語版 | temozolomide
Temozolomide, (TMZ) (brand names Temodar and Temodal and Temcad) is an oral chemotherapy drug. It is an alkylating agent used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.〔〔NICE (NICE technology appraisal guidance [TA23]: Guidance on the use of temozolomide for the treatment of recurrent malignant glioma (brain cancer) ) Published date: April 200〕 ==Indications==
* Nitrosourea- and procarbazine-refractory anaplastic astrocytoma〔(Temodar label ) Last updated Feb 2011〕〔 * Newly diagnosed glioblastoma multiforme〔
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