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thrombolysis : ウィキペディア英語版 | thrombolysis
Thrombolysis is the breakdown (''lysis'') of blood clots by pharmacological means, and commonly called ''clot busting''. It works by stimulating secondary fibrinolysis by plasmin through infusion of analogs of tissue plasminogen activator (tPA), the protein that normally activates plasmin. ==Agents== Thrombolysis mainly involves the use of thrombolytic drugs, which dissolve blood clots. These drugs are either derived from ''Streptococcus'' species, or, more recently, using recombinant biotechnology whereby tPA is manufactured by bacteria, resulting in a recombinant tissue plasminogen activator or rtPA. Some commonly used thrombolytics are: * Streptokinase * Urokinase * Recombinant tissue plasminogen activators * * Alteplase (rtPA) * * Reteplase * * Tenecteplase
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