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tolaasin
Tolaasin, a secretion by ''Pseudomonas tolaasii'', is the cause of bacterial brown blotch disease of edible mushrooms. Tolaasin is a 1985 Da lipodepsipeptide non-host specific toxin. In addition to forming an amphipathic left handed alpha-helix in a hydrophobic environment, the toxin has been shown to form Zn2+-sensitive voltage-gated ion channels in planar lipid bilayers and to catalyze erythrocyte lysis by a colloid osmotic mechanism. At high concentrations, tolaasin acts as a detergent that is able to directly dissolve eukaryotic membranes().
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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