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transfersome
Transfersome is a trademark registered by the German company IDEA AG, which refers to its proprietary drug delivery technology. The name means “carrying body” and is derived from the Latin word 'transferre', meaning 'to carry across', and the Greek word 'soma', meaning 'a body'. A ''Transfersome'' carrier is an artificial vesicle designed to exhibit the characteristics of a cell vesicle or a cell engaged in exocytosis, and thus suitable for controlled and, potentially, targeted drug delivery.
==Discovery==
The term ''Transfersome'' and the underlying concept were introduced in 1991 by Gregor Cevc. Numerous groups have since been working with similar carriers, frequently using different names (e.g., elastic vesicle, flexible vesicle, Ethosome, etc.) to describe them.
In a broader sense, a ''Transfersome'' is a highly adaptable, stress-responsive complex aggregate. The form preferred by researchers and pharmacologists is an ultradeformable vesicle possessing an aqueous core surrounded by the complex lipid bilayer. Interdependencies inherent in the local composition and shape of the bilayer makes the vesicle both self-regulating and self-optimizing. This enables the ''Transfersome'' to cross various transport barriers efficiently, and then act as a Drug carrier for non-invasive targeted drug delivery and sustained release of therapeutic agents.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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