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triclocarban : ウィキペディア英語版
triclocarban

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Triclocarban is an antibacterial agent common in personal care products like soaps and lotions as well as in the medical field, for which it was originally developed.〔"Anti-bacterial personal hygiene products may not be worth potential risks." UC Davis Health System Feature Story: Anti-bacterial personal hygiene products.... UC Davis Health System, n.d. Web. 12 Mar. 2014. .〕 Studies on its antibacterial qualities and mechanisms are growing. Research suggests that it is similar in its mechanism to triclosan and is effective in fighting infections by targeting the growth of bacteria such as ''Staphylococcus aureus''. Additional research seeks to understand its potential for causing antibacterial resistance and its effects on organismal and environmental health.
==Uses==
Triclocarban has been used as an antimicrobial and antifungal compound since the 1960s.〔Orsi, Mario, Massimo Noro, and Jonathan Essex. "Dual-resolution molecular dynamics simulation of antimicrobials in biomembranes." Journal of The Royal Society Interface 8.59 (2010): 826-841. PubMed Central. Web. 17 Feb. 2014. http://www.ncbi.nlm.nih.gov.proxy.bc.edu/pmc/articles/PMC3104353/〕 It is commonly found in personal care products as antimicrobials such as in soaps, lotions, deodorants, toothpaste, and plastic.〔Brausch, John, and Gary Rand. "A review of personal care products in the aquatic environment: Environmental concentrations and toxicity." Chemosphere 82.11 (2011): 1518-1532. ScienceDirect. Web. 17 Feb. 2014. http://ac.els-cdn.com/S0045653510013007/1-s2.0-S0045653510013007-main.pdf?_tid=c685833c-9812-11e3-87db-00000aab0f6c&acdnat=1392669395_a731b9c664c4e98737d93755500c43dd〕 About 80% of all antimicrobial bar soap sold in the United States contains triclocarban.〔 Additionally, the United States spends nearly 1 billion dollars annually on products containing triclocarban and triclosan.〔Ahn, Ki Chang, Bin Zhao, Shirley Gee, Bruce Hammock, Jiangang Chen, Gennady Cherednichenko, Enio Sanmarti, Michael Denison, Bill Lasley, Isaac Pessah, Dietmar Kultz, and Daniel Chang. "In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens." Environmental Health Perspectives 116.9 (2008): 1203-1210. PubMed Central. Web. 17 Feb. 2014. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535623/〕
In December 2013, the Food and Drug Administration required all companies to prove within the next year, that triclocarban is not harmful to consumers. In recent years, companies like Johnson & Johnson, Procter & Gamble, Colgate-Palmolive, and Avon have begun phasing out chemical use due to health concerns.〔Westervelt, Amy, http://www.theguardian.com/sustainable-business/avon-remove-triclosan-product-cosmetic-chemicals〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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