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tylosin
Tylosin is a bacteriostat feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms.〔''(Antimicrobial Therapy in Veterinary Medicine )'', by Steeve Giguere, P. M. Dowling, ISBN 978-0-8138-0656-3〕 It is found naturally as a fermentation product of ''Streptomyces fradiae''.〔(Tylosin ), marvistavet.com〕 It is a macrolide antibiotic. Tylosin is used in veterinary medicine to treat bacterial infections in a wide range of species and has a high margin of safety.〔Tylan 200 Injectable - Product data sheet PA9063DENZP - Elanco Animal Health〕 It has also been used as a growth promotant in some species, and as a treatment for colitis in companion animals.〔 == Mode of action ==
Like other macrolides, tylosin has a bacteriostatic effect on susceptible organisms, caused by inhibition of protein synthesis through binding to the 50S subunit of the bacterial ribosome.
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