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Drugbox | IUPAC_name = (2''S'')-2- " TITLE="(2''S'')-2- "> image = Tynorphin.svg opioid peptide which is a potent and competitive inhibitor of the enkephalinase class of enzymes which break down the endogenous enkephalin peptides.〔cite journal | author = Yamamoto Y, Hashimoto J, Shimamura M, Yamaguchi T, Hazato T | title = Characterization of tynorphin, a potent endogenous inhibitor of dipeptidyl peptidaseIII | journal = Peptides | volume = 21 | issue = 4 | pages = 503–8 |date=April 2000 | pmid = 10822105 | doi = 10.1016/S0196-9781(00)00174-1| url = http://linkinghub.elsevier.com/retrieve/pii/S0196978100001741}}〕 It specifically inactivates dipeptidyl aminopeptidase III (DPP3) with very high efficacy, but also inhibits neutral endopeptidase (NEP), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE) to a lesser extent.〔 It has a pentapeptide structure with the amino acid sequence Val-Val-Tyr-Pro-Trp. Tynorphin was discovered in an attempt to develop an enkephalinase inhibitor of greater potency than ()].〔 == See also == * Enkephalinase inhibitor 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「tynorphin」の詳細全文を読む スポンサード リンク
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